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The POGIL typically divides the immune response into three distinct "lines." Understanding these is the first step to answering the model questions correctly. 1. First Line: Physical and Chemical Barriers (Innate)

This is your body's "wall." It is non-specific, meaning it treats every invader the same way. A physical barrier that keeps pathogens out. Mucous Membranes: Traps pathogens in sticky fluid.