The story begins with the death of the Altman family patriarch, Mort Altman, who leaves behind a wife, Hilary (Jane Fonda), and four grown children: Judah (Adam Driver), the eldest son, who is struggling to come to terms with his father's passing; Natalie (Rose Byrne), the free-spirited and rebellious daughter; Charlie (Corey Stoll), the middle child, who is trying to find his place in the world; and Wendy (Abigail Spencer), the youngest daughter, who is dealing with her own share of emotional baggage.