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The first step in resolving the error is to ensure that you are running the latest version of Adobe Reader. To update Adobe Reader:

When you get the incompatibility error, Adobe Reader is essentially telling you: "Something on your PC is stopping me from locking myself in the safe room. I can come out to work, but I will be unsafe."

Several factors can cause this error, including:

The "Protected Mode" error usually occurs when Adobe Acrobat Reader’s security "sandbox" conflicts with your operating system settings, specific antivirus programs, or Windows compatibility modes Adobe Help Center Quick Fix: Disable Protected Mode