Since its first description in 2018 (in Salmonella enterica serotype Typhimurium from a patient in the United States and a food sample in Italy), mcr-9 has been identified globally. Its primary reservoirs include:
Furthermore, the presence of MCR-9 in CRE isolates highlights the need for enhanced infection control practices in healthcare settings. The spread of resistant bacteria within hospitals and communities can be prevented through strict adherence to hygiene protocols, improved antibiotic stewardship, and the implementation of robust surveillance systems. Since its first description in 2018 (in Salmonella
While there are now ten known variants (mcr-1 to mcr-10), is particularly notable for being the second most prevalent variant globally, trailing only the original mcr-1. The Phenomenon of "Silent" Dissemination improved antibiotic stewardship