A: Not officially. The ASMedia 1042 chip on this board does not support UASP. You need a PCIe USB 3.2 add-on card for that feature.
not showing up in Device Manager, or are you preparing for a fresh installation M5A78L-M Windows 10 support? - PCPartPicker asus m5a78l-m usb3 drivers windows 10
The USB 3.0 controller on this board is part of the AMD chipset architecture. The best solution is to install the AMD Chipset Drivers, which are more recent than the specific ASUS packages. A: Not officially
After changing BIOS settings, from scratch. asus m5a78l-m usb3 drivers windows 10