This is almost always due to the USB-to-Serial adapter driver. Windows 10 Update may have automatically “updated” your driver to a generic Microsoft version that doesn’t support legacy Prolific chips. Roll back the driver or replace the adapter.
The software used to configure the PBX——does not sit in your Device Manager as a driver. Instead, it is a standard Windows application that communicates over a protocol (serial or TCP/IP). The "driver" you are looking for is actually a COM port emulator or a network protocol enabler . Kx-tes824 Windows 10 Driver