GURPS Transhuman Space explores a number of themes that are relevant to the transhumanist movement, including:
The game is set in the year 2170, where humanity has established colonies on the moon, Mars, and other planets in the solar system. The solar system is divided into various factions, including the Solarian Union, a loose confederation of Earth-based governments; the Mars Colonies, a group of independent city-states; and the Jupiter colonies, a collection of habitats and space-based societies. The setting is richly detailed, with a focus on the implications of advanced technology on human society. gurps transhuman space pdf