RetroArch is a front-end that runs "cores" (emulators). For 3DO, it uses the Opera core (a fork of 4DO) or the older FreeDO core.
The 3DO was technically ahead of its time. While it lacked the 3D polygon-pushing power of the PlayStation, it excelled in texture mapping and full-motion video (FMV) playback. Many games released for the 3DO are still considered the definitive versions, even when compared to their later PlayStation or Saturn ports. 3DO Interactive Multiplayer Emulators for Android
Choose 4DO if you are a retro purist who already has a BIOS collection and prefers open-source software over freemium apps. RetroArch is a front-end that runs "cores" (emulators)
The core prioritizes accuracy over speed, which is noble but impractical on Android where thermal throttling is real. 3DO Interactive Multiplayer Emulators for Android