Neuroanatomy is not just about isolated "hubs" but also the "wires." White matter

If you hold a human brain, you first notice the (wrinkled outer shell), the cerebellum (small, tight "mini-brain" at the back), and the brainstem (the stalk connecting to the spinal cord).

Composed of the midbrain, pons, and medulla , it connects the brain to the spinal cord. It regulates vital functions such as breathing, heart rate, and sleep-wake cycles.

Occupying only 10% of the brain’s volume but containing over 50% of its neurons, the cerebellum is the master of coordination. It compares the intended movement (from the motor cortex) with the actual movement (from proprioceptors) and sends corrective signals. It is also involved in cognitive flexibility and timing.

For decades, glial cells were viewed merely as the "glue" (from the Greek glia ) that held neurons together. Modern neuroanatomy has revealed they are essential partners. Astrocytes maintain the blood-brain barrier and regulate chemical environment; oligodendrocytes insulate axons in the central nervous system with myelin, speeding up transmission; and microglia act as the brain's immune defense. The architecture of the brain is a partnership between the signaling neurons and the supportive glia.